With United already leading 5-0 after the away leg, plenty of fringe players can be expected to line up at Old Trafford.
Still, the likes of Odion Ighalo, Brandon Williams, Sergio Romero and Jesse Lingard have all produced in this competition and anyone starting will be keen to impress enough to play their part in Monday’s quarter-final and perhaps beyond.
As for Austrian side LASK, they are effectively in the middle of pre-season, a league campaign which tailed off badly having ended a month ago.
Having led the Bundesliga at the post-lockdown split, LASK went 3-1-6 after it – and suffered a points deduction – to finish only fourth.
That run cost boss Valerien Ismael his job and now Dominik Thalhammer is in charge – this will be his first competitive game.
At the weekend his new side played a friendly against Slovakian side Senica and lost 2-0. All 11 players were changed at half time with both goals coming in the second half.
In reality, LASK’s Europa campaign is over and Thalhammer will be keen to use this as another stepping stone towards the start of the 2020/21 campaign.
United are just 1/4 to win and given both the strength of their squad and the fact that they played only 10 days ago, they should do.
Perhaps the best way of getting some value is to back them to win both halves at 6/4.
They’ve managed that in five of their last seven games at Old Trafford, as well as in the first leg.
For something juicier, 3-0 in the correct score market – a 13/2 shot – looks around about what can be expected, although it may well pay to wait for the team news.
*All prices correct at the time of writing and subject to change